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Brain Res 1505:6167

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2023Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial

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Melanotan II is a non-selective pan-melanocortin agonist (MC1R+MC3R+MC4R+MC5R), whereas PT-141 (Bremelanotide) is more selective for MC3R/MC4R with minimal MC1R activity

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